As per my understanding you want to know about the 1. Total knee replacement and 2. IVF. 1. Total Knee replacement surgery is done to replace the damaged joints so patient is relieved of symptoms. The knee joint with an artificial knee called prosthesis made of metal, plastic, and ceramic. It helps to restore function of the damaged knee and relieve arthritis pain. Knee replacement surgery is advised if the pain is interfering with your daily activities and negatively affecting your quality of life. Generalized fitness is important here. Total knee replacement is being done on the patients routinely, but some of the risks associated with this surgery are infection, blood clots, failure of the artificial joint, heart attack etc. Post surgery care, rehabilitation is very important. Consult an orthopedic. 2. In vitro fertilization (IVF) is a process of fertilization, where an egg is combined with sperm and fertilized outside the body, in a liquid in a laboratory. Consult Best Gynecologists in Mumbai, or any other city, who on evaluation will guide through the treatment. Hope our answer helps you.